On 29 December 1999 Mexico and Uruguay signed an Economic Complementation Agreement, which was deposited with the ALADI as ACE No 5. This agreement entered into force on 1 March 2001.

On 5 July 2002, Mexico and the member states of MERCOSUR -- Argentina, Brazil, Paraguay and Uruguay -- signed an ALADI framework agreement (ACE No 54) that aims to create a free trade area. In August of that year Mexico and Uruguay initiated negotiations towards a free trade agreement. The Mexico-Uruguay free trade agreement was signed during the XIII Iberoamerican Summit on 15 November 2003 in Santa Cruz de la Sierra, Bolivia.

Mexico and Uruguay signed the Second Protocol Amending the agreement on November 27, 2019. Mexico and Uruguay signed the Third Additional Protocol to the Free Trade Agreement on November 20, 2020.

Documents relating to the negotiations
20 November 2020	Mexico and Uruguay sign Third Additional Protocol to their FTA
27 November 2019	Mexico and Uruguay sign Second Amending Protocol to their FTA
15 November 2003	Signing of Mexico-Uruguay Free Trade Agreement
Source: Ministerio de Relaciones Exteriores, Uruguay; Secretaría General de la Asociación Latinoamericana de Integración (ALADI)

The Mexico-Uruguay free trade agreement was deposited with the ALADI (as ACE No 60) on 25 June 2004. The text of the agreement was published in the Mexican official gazette on 14 July 2004 and the agreement went into effect on 15 July 2004.

This agreement was incorporated into the countries legal system's by means of Joint Note No. 053/04 and No. 302/04 of 17 June 2004 (CR/di 1797).

Documents relating to the entry into force
15 July 2004	Mexico-Uruguay FTA enters into force
14 July 2004	Text of Mexico-Uruguay FTA published in Mexican Diario Oficial de la Federación
25 June 2004	Mexico and Uruguay deposit agreement in ALADI
Sources: Secretaría General de la Asociación Latinoamericana de Integración (ALADI); Presidencia de la República de México

On 26 October 2007 Mexico enacted modifications to the free trade agreement.

The Administrative Commission of the agreement had four meetings. The fourth meeting took place in May 2012, in Montevideo, Uruguay. The Sixth meeting took place on November 21, 2017. The Seventh meeting was held in Mexico as part of the commemoration of the 15th anniversary of the Mexico-Uruguay FTA.

Documents relating to the implementation of the agreement
17 September 2020	Eighth meeting of the Mexico-Uruguay Free Trade Commission
02-03 September 2019	Seventh meeting of the Mexico-Uruguay Free Trade Administrative Commission
21 November 2017	Sixth meeting of the Mexico-Uruguay Free Trade Administrative Commission
07 September 2016	Fifth meeting of the Administrative Commission
May 2012	Fourth meeting of the Administrative Commission
26 October 2007	Mexico enacts modifications to the Mexico-Uruguay FTA
Sources: Secretaría de Economía de la República de México; Ministerio de Relaciones Exteriores, Uruguay

• Ministerio de Relaciones Exteriores, Uruguay
• Presidencia de la República de México
• Secretaría de Economía de México
• Secretaría General de la Asociación Latinoamericana de Integración (ALADI)